My dad went for a prp injection on both knees about 3 months ago. Immediately after the injection he felt ill and was unable to walk. Prior to the injection he was able to walk slowly. He has been having fever every night only since the injection & his knee becomes warm. He has been admitted twice to the hospital and treated with antibiotics but his fever wont go. All test has turned out to be negative and doctors are unable to diagnose the cause of the fever. He is still unable to walk unassisted.
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Fever after PRP injection at knee
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If culture is negative, get an infectious disease consultant and recommend extensive arthroscopic irrigation and debridement with tissue biopsy. During arthroscopy the degree of arthritis will give you an idea how badly damaged the articular cartilage. If it is severe, then nothing you do will decrease the pain and he may require a Total Knee Replacement if infection is completely eradicated.