What are the risks involved with an early paternity test for someone with a high risk pregnancy?
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Paternity Test While Pregnant
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In technical terms, that test -if performed in the first trimester - is about the Chorionic villus sampling (CVS), a form of slightly invasive procedure that entails sampling of the chorionic villus (prototype of the placental tissue) and testing it commonly with fluorescence in situ hybridization (FISH) or polymerase chain reaction (PCR). CVS takes place at 10–12 weeks' gestation. Amniocentesis or percutaneous umbilical cord blood sampling is performed after 12 gestation weeks.
CVS is performed either via transcervical or transabdominal manners. You will be asked to sign an informed consent form where it will be thoroughly described that in the transcervical approach an ultrasound will guide a Portex catheter of 1.5mm in diameter through the cervix to the placental substance. The chorionic villi cells will be gently aspirated into the catheter.
NOTE 1: Negative cervical cultures for gonorrhea and chlamydia should be obtained before the procedure.
In transabdominal method, an ultrasound will guide a 17-gauge spinal needle through the abdomen to the edge of placenta. A 19-20-gauge spinal needle will be then inserted through the first needle and passed into the placenta without penetrating the amniotic sac. The needle will draw a sample of tissue which is aspirated with
a syringe. This procedure is similar to amniocentesis and its adequacy is ascertained under a dissecting microscope.
The procedure is slightly invasive, but the complications are rare: miscarriage - 0.5 - 1%; premature rupture of membranes - 1-2%; fetal direct injury -less than 1%, bleeding - 1%; isoimmunization - less than 1%, infection -less than 1%, fetal limb reduction defects -1%, others.
NOTE 2: . In Rh-negative women an injection of Rh-Ig should be given in advance.
Think twice against the benefit/risk ratio. Good luck and happy motherhood.
CVS is performed either via transcervical or transabdominal manners. You will be asked to sign an informed consent form where it will be thoroughly described that in the transcervical approach an ultrasound will guide a Portex catheter of 1.5mm in diameter through the cervix to the placental substance. The chorionic villi cells will be gently aspirated into the catheter.
NOTE 1: Negative cervical cultures for gonorrhea and chlamydia should be obtained before the procedure.
In transabdominal method, an ultrasound will guide a 17-gauge spinal needle through the abdomen to the edge of placenta. A 19-20-gauge spinal needle will be then inserted through the first needle and passed into the placenta without penetrating the amniotic sac. The needle will draw a sample of tissue which is aspirated with
a syringe. This procedure is similar to amniocentesis and its adequacy is ascertained under a dissecting microscope.
The procedure is slightly invasive, but the complications are rare: miscarriage - 0.5 - 1%; premature rupture of membranes - 1-2%; fetal direct injury -less than 1%, bleeding - 1%; isoimmunization - less than 1%, infection -less than 1%, fetal limb reduction defects -1%, others.
NOTE 2: . In Rh-negative women an injection of Rh-Ig should be given in advance.
Think twice against the benefit/risk ratio. Good luck and happy motherhood.
The high risk care provider
can explore this possibility.
can explore this possibility.