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Molly Maloof, MD

Director of Clinical Content
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My wife, 6 weeks pregnant was taking 5 mg folic acid pills a day for 10 days

We are in thailand and a local clinic reccomended this. I just checked the recomendations for folic acid and it recomends 500 micrograms a day or 10 times less.

Should I be concerned? We are planning on getting back to our contry in 3 weeks to start going to the doctor about the pregnancy. She is not currently experiencing any abnormal symptoms.
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Featured Answer

2 UpVoted this answer Kevin W. Hamburger, MD OB/GYN, Sioux City
i would not be concerned. Folic acid is a water soluable vitamin and if you take too much it will just be excreted by your kidneys. Congratulations on the pregnancy.
1 UpVoted this answer Compass Clinic - Dallas Addiction Medicine, Lewisville
It does sound high. Fortunately, though, this is a vitamin that your body only takes up as much as it needs, so there is no risk of overdose.

Congratulations, and great travels!
1 UpVoted this answer Randy Kiriluk, MD Family Medicine, Wesley Chapel
5 mgrs or 5,000 micrograms of folic acid daily is too high of a dose.The recommended daily intake (RDI) set by the FDA is 600 micrograms or 0.6 miligrams. In pregnant patients that recommendation is increased by 400 micrograms to a total of 1,000 or 1 milligram. Although toxicity is low for being a water soluble vitamin that is excreted easily in urine,there really is no need to take 5 mgrs daily. In the United States prenatal vitamins over the counter have from 600 to 800 mcgrs and prescription ones have 1,000. Just stay within the recommended doses and she will be ok.
Richard Nuila-Crouse
1 UpVoted this answer
Continue prenatal vitamins
Shwetanshu Shukla
there is no toxic dose for any of the B vitamins. the only way to be hurt by them would be a 100 lb sack falling on your head.

for even the oil soluble vitamins....one has to go way off the reservation to build up a toxic dose. for instance, vitamin D was in the PDR over 50 years ago at a starting dose of 150,000 iu. to treat autoimmune disease and asthma. doses crept up to a million units a day before some people had symptoms....easily reversed by discontinuing the ridiculous dose.

off on a tangent...this begs the question; why don't we use such low toxicity substances to treat these conditions today? ........humm?....

anyway, the doses of folic acid mentioned won't hurt anything but are likely well beyond therapeutic levels.
That is still considered a safe dose, in fact we use a dose similar to that in women with increased risk of neural tube defects to decrease the risk of recurrence.
Nima Goharkhay
It is recommended for a pregnant woman to take 600-1,000 micrograms (0.6 - 1 milligrams) of folic acid daily during pregnancy. However, if there is a family history of neural tube defects the recommendation is 5 mg daily. Folic acid is a water-soluble vitamin and 5 mg of folic acid daily has not shown to be harmful for the mother or the baby..
While that is quite a high dose, I would not worry too much. Folate is a water soluble vitamin and does not generally accumulate in your body. The excess is excreted in the urine. The lower dose you read about is for non-pregnant patients. She should take 800 to 1 mg per day. That amount has been shown to prevent neural tube defects, and is what is contained in Prenatal Vitamins.
Starting on a prenatal vitamin will provide her with adequate dose. Most prenatal vitamins have 800 micrograms of folic acid. People at high risk for neural tube defects need to take more.
Roya Rakhshani
in a normal pregnancy, I usually advise 400mcg/day., but in presence of a family history of neural tube defects , 5 mg is recommended.She should revert to 400-500 mcg daily for her normal pregnancy along with her normal pre-natal vitamins
Rajen Ramgoolam