Persistent cough for years. Have seen Ent, allergist and pullmonary.post nasal drip, mucous... plus help?
Anonymous Patient
I disagree with your doctor, losartan may cause chronic cough though the mechanism of this is unclear (it does not affect substance P and the kinin system as ACE-Inhibitors do) but there are numerous case reports of chronic cough associated with losartan (cozaar) and even the package insert mentions about 3-4% incidence of cough with this medicine, If your cough can be described as an annoying tickle and a feeling that something is constantly stuck in throat and thus need to cough to clear it out, then I am very suspicious of the losartan (this is the classic description I have gotten from patients with ACE-Inhibitor cough and reports of losartan cough describe very similar symptomatology. Unfortunately, I do NOT recommend changing a medicine for your BP without the clear permission and involvement of your prescribing doctor, but I would suggest working with him/her to find an alternate class of anti-hypertensive medicine to take so you can stop the losartan for at least 4 weeks, as chronic cough associated with these medicines can sometimes take that long to fully resolve. In my experience and from papers I have read, you will usually feel SOME change in nature of cough and some reduction in sensations leading to cough within at least one week of totally stopping this medicine. I agree, losartan causing this cough is far rarer than a typical ACE-Inhibitor, but it is certainly a known cause for chronic annoying cough and before I would chase other less common causes, such as tic/habit cough which is next on my list of causes based on your limited cough description, I would certainly try changing this medicine. If the medicine is the cause, then no matter what else you take or do, in my experience, the cough will NOT respond. I wish you luck and good health.